Description

3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Ylamine Hydrochloride, 98+% C11H14Cl2F3N3, Mw: 316.15 is a high-purity, complex heterocyclic amine hydrochloride salt, distinguished by its trifluoromethyl and chloro substituents. This compound is a critical advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients, where its structural motifs are leveraged to modulate potency, metabolic stability, and bioavailability. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Chemical Biology Probe: Serves as a precursor for labeled compounds or molecular probes used in target identification and validation studies.
• Ligand and Catalyst Development: The amine functionality and complex bipyridinyl structure make it a candidate for developing new ligands in asymmetric catalysis.
• Material Science Research: Potential intermediate for synthesizing specialized monomers or functionalized polymers with unique electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Ylamine Hydrochloride, 98+%
CAS No.	1185313-62-5
Molecular Formula	C11H14Cl2F3N3
Molecular Weight	316.15 g/mol
Synonyms	3-Amino-3'--chloro-5'-trifluoromethyl-1,2,3,4-tetrahydro-2,2'-bipyridine Hydrochloride; 3'-Chloro-5'-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-[1,2'-bipyridin]-3-amine hydrochloride; 3-Amino-3'-chloro-5'-trifluoromethyl-1,2,3,4-tetrahydro-2,2'-bipyridine HCl; 3'-Chloro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3-amine HCl; CAS 1185313-62-5
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.