Description

3-Nitro-2-(Piperidin-4-Yloxy)-Pyridine Hydrochloride is a high-purity (98+%) organic salt with the molecular formula C10H14ClN3O3 and a molecular weight of 259.69 g/mol. This compound serves as a critical building block (intermediate) in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable supply of high-quality, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its nitro-pyridine and piperidine motifs.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study biological pathways and protein interactions.
• Ligand and Catalyst Development: The structural features make it suitable for developing novel ligands for metal catalysis or organocatalysts.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies and novel heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized compounds for clients.

Basic Information

Item	Details
Product Name	3-Nitro-2-(Piperidin-4-Yloxy)-Pyridine Hydrochloride, 98+%
CAS No.	1185313-15-8
Molecular Formula	C10H14ClN3O3
Molecular Weight	259.69 g/mol
Synonyms	3-Nitro-2-(4-piperidyloxy)pyridine hydrochloride; 2-(Piperidin-4-yloxy)-3-nitropyridine HCl; 3-Nitro-2-(piperidin-4-yloxy)pyridine HCl; Pyridine, 3-nitro-2-(4-piperidinyloxy)-, hydrochloride; 1185313-15-8; 3-Nitro-2-(4-piperidinoloxy)pyridine hydrochloride; 2-(4-Piperidyloxy)-3-nitropyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitro-2-(Piperidin-4-Yloxy)-Pyridine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.