Description

2-Chloro-5-(Piperidin-4-Yloxymethyl)-Pyridine Dihydrochloride is a high-purity (98+%) organic salt with the molecular formula C11H17Cl3N2O and a molecular weight of 299.62. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its piperidine and pyridine motifs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function and receptor interactions.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of complex drug candidates.
• Custom Synthesis: Starting material for the contract synthesis of specialized, non-commercially available compounds for research purposes.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Piperidin-4-Yloxymethyl)-Pyridine Dihydrochloride, 98+%
CAS No.	1185312-88-2
Molecular Formula	C11H17Cl3N2O
Molecular Weight	299.62 g/mol
Synonyms	2-Chloro-5-((piperidin-4-yloxy)methyl)pyridine dihydrochloride; 2-Chloro-5-[(4-piperidinyloxy)methyl]pyridine dihydrochloride; 4-((6-Chloropyridin-3-yl)methoxy)piperidine dihydrochloride; 2-Chloro-5-(piperidin-4-yloxymethyl)pyridine hydrochloride (1:2); 2-Chloro-5-(4-piperidyloxymethyl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Piperidin-4-Yloxymethyl)-Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the stated purity of 98+% and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.