Description

3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Ylamine Hydrochloride, 98+% C11H14Cl2F3N3, Mw: 316.15 is a high-purity, complex heterocyclic amine hydrochloride salt, serving as a critical advanced pharmaceutical intermediate (API) and key building block in modern organic synthesis. Its molecular architecture, featuring a chlorinated and trifluoromethylated bipyridinyl core, makes it invaluable for constructing molecules with specific bioactivity and physicochemical properties. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active ingredients, particularly in therapeutic areas requiring sophisticated chemical scaffolds.

Application

This specialized intermediate is designed for advanced chemical synthesis and research applications, including:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, complex organic molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3'-Chloro-5'-Trifluoromethyl-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Ylamine Hydrochloride, 98+%
CAS No.	1185310-97-7
Molecular Formula	C11H14Cl2F3N3
Molecular Weight	316.15 g/mol
Synonyms	4-Amino-3'-chloro-5'-(trifluoromethyl)-3,4,5,6-tetrahydro-2H-[1,2'-bipyridinyl] hydrochloride; 3'-Chloro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-amine hydrochloride; 1185310-97-7; 4-Amino-3'-chloro-5'-(trifluoromethyl)-1,2,3,6-tetrahydropyrido[2,1-c][1,4]oxazine hydrochloride (alternative fused system representation); Tetrahydro-bipyridinylamine hydrochloride derivative.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and conformity to specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production requirements. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.