Description

2-(Piperidin-4-Yloxy)-Nicotinonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: Employed by CROs and CDMOs for the contract manufacturing of proprietary compounds and reference standards.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	2-(Piperidin-4-Yloxy)-Nicotinonitrile Hydrochloride
CAS No.	1185310-20-6
Molecular Formula	C11H14N3O·HCl
Molecular Weight	239.71 g/mol
Synonyms	2-((Piperidin-4-yl)oxy)nicotinonitrile hydrochloride; Nicotinonitrile, 2-(4-piperidinyloxy)-, hydrochloride; 2-(4-Piperidyloxy)nicotinonitrile HCl; 2-(Piperidin-4-yloxy)pyridine-3-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-4-Yloxy)-Nicotinonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing comprehensive test results, including assay and impurity profiles, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.