Description

3-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure (C12H19Cl2N3O2, Mw: 308.21). This compound is critical for research and development in medicinal chemistry, particularly for constructing complex nitrogen-containing heterocycles. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis: Acts as a precursor for chelating agents and ligands used in catalysis and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API synthesis.

Basic Information

Product Name	3-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester dihydrochloride
CAS No.	1185309-86-7
Molecular Formula	C12H19Cl2N3O2
Molecular Weight	308.21 g/mol
Synonyms	Methyl 3-amino-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine]-3'-carboxylate dihydrochloride; 3'-Carbomethoxy-3-amino-1,2,3,6-tetrahydropyrido[2,3-b]pyridine dihydrochloride; 3-Amino-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester hydrochloride (1:2); 3-Amino-1,2,3,6-tetrahydro-2H-[1,2']bipyridinyl-3'-carboxylic acid methyl ester dihydrochloride
EINECS	Contact for details

Quality Control

Our 98+% purity grade of this intermediate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.