Description

5-Nitro-2-(4-Piperidinyloxy)Pyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1185309-69-6. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design and synthesis of potential kinase inhibitors for targeted cancer therapies.
• Chemical Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and quality control in chemical production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	5-Nitro-2-(4-Piperidinyloxy)Pyridine Hydrochloride
CAS No.	1185309-69-6
Molecular Formula	C10H14N3O3·HCl
Molecular Weight	261.70 g/mol (Free base: 225.24 g/mol)
Synonyms	5-Nitro-2-(4-piperidinyloxy)pyridine hydrochloride; 2-(4-Piperidinyloxy)-5-nitropyridine hydrochloride; 5-Nitro-2-(piperidin-4-yloxy)pyridine HCl; 4-((5-Nitropyridin-2-yl)oxy)piperidine hydrochloride; 1185309-69-6; 5-Nitro-2-(4-piperidyloxy)pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(4-Piperidinyloxy)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.