Description

2-[(Piperidin-4-Ylmethyl)-Amino]-Nicotinonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C12H17ClN4 and a molecular weight of 252.74. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive molecules.
• Chemical Synthesis Building Block: Employed in the construction of complex piperidine- and pyridine-containing heterocycles for various applications.
• Biochemical Research: May serve as a tool compound or ligand in biochemical assays and receptor binding studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-[(Piperidin-4-Ylmethyl)-Amino]-Nicotinonitrile Hydrochloride
CAS No.	1185307-76-9
Molecular Formula	C12H17ClN4
Molecular Weight	252.74 g/mol
Synonyms	2-[(4-Piperidinylmethyl)amino]-3-pyridinecarbonitrile hydrochloride; 2-((Piperidin-4-ylmethyl)amino)nicotinonitrile HCl; Nicotinonitrile, 2-[(4-piperidinylmethyl)amino]-, hydrochloride; 2-[(Piperidin-4-Ylmethyl)-Amino]-Nicotinonitrile HCl; 2-((4-Piperidylmethyl)amino)nicotinonitrile hydrochloride; 2-[(4-Piperidinylmethyl)amino]nicotinonitrile monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-[(Piperidin-4-Ylmethyl)-Amino]-Nicotinonitrile Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.