Description

2-(Piperidin-3-Ylamino)-Nicotinic Acid Methyl Ester Dihydrochloride, 98+% C12H19Cl2N3O2, Mw: 308.21 is a high-purity, advanced pharmaceutical intermediate with the CAS number 1185307-66-7. This compound is valued for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its piperidine and nicotinic acid ester motifs.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and receptor interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	2-(Piperidin-3-Ylamino)-Nicotinic Acid Methyl Ester Dihydrochloride
CAS No.	1185307-66-7
Molecular Formula	C12H19Cl2N3O2
Molecular Weight	308.21 g/mol
Synonyms	Methyl 2-[(3-piperidinyl)amino]nicotinate dihydrochloride; 2-[(Piperidin-3-yl)amino]pyridine-3-carboxylic acid methyl ester dihydrochloride; 2-(3-Piperidinylamino)nicotinic acid methyl ester dihydrochloride; Methyl 2-(3-piperidinylamino)nicotinate dihydrochloride; 2-(Piperidin-3-ylamino)nicotinic acid methyl ester hydrochloride (1:2); Nicotinic acid, 2-[(3-piperidinyl)amino]-, methyl ester, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-3-Ylamino)-Nicotinic Acid Methyl Ester Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure the 98+% minimum purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.