Description

(2-{1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Yl}Ethyl)Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1185302-39-9. This compound is a critical building block in modern medicinal chemistry, valued for its structural complexity and functional versatility. It is primarily sought after by research institutions and pharmaceutical manufacturers for the development and synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Serves as a core scaffold for constructing molecules with potential pharmacological activity in preclinical and clinical research.
• Chemical Synthesis: Employed in organic synthesis for constructing piperidine and sulfonamide-containing compounds with specific stereochemistry.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for clients.

Basic Information

Product Name	(2-{1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Yl}Ethyl)Amine Hydrochloride
CAS No.	1185302-39-9
Molecular Formula	C15H24N2O2S • HCl
Molecular Weight	332.89 g/mol (Free base: 296.43 g/mol)
Synonyms	4-[2-Aminoethyl]-1-(4-methylphenylsulfonyl)piperidine hydrochloride; 1-(p-Toluenesulfonyl)-4-(2-aminoethyl)piperidine hydrochloride; 4-(2-Aminoethyl)-1-tosylpiperidine HCl; N-[2-(1-Tosyl-4-piperidinyl)ethyl]amine hydrochloride; 1-Tosyl-4-(2-aminoethyl)piperidine hydrochloride; (2-(1-Tosylpiperidin-4-yl)ethyl)amine hydrochloride; 4-(2-Aminoethyl)-1-[(4-methylphenyl)sulfonyl]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-{1-[(4-Methylphenyl)Sulfonyl]Piperidin-4-Yl}Ethyl)Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.