Description

3-(Piperidin-4-Yl)-1H-Pyrazolo[3,4-B]Pyridine is a high-purity, heterocyclic organic compound featuring a fused pyrazolopyridine core substituted with a piperidine moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for medicinal chemistry programs. It is primarily utilized by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and as a key building block in drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probe: Serves as a core scaffold for developing tool compounds to study biological pathways and target validation.
• Organic Synthesis: Employed as a versatile precursor for constructing complex nitrogen-containing heterocycles in academic and industrial laboratories.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	3-(Piperidin-4-Yl)-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1185192-81-7
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	3-(4-Piperidinyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-(4-piperidinyl)-; 3-(Piperidin-4-yl)-1H-pyrazolo[3,4-b]pyridine; 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-pyrazolo[3,4-b]pyridine (tautomer); 1185192-81-7; Pyrazolopyridine-piperidine derivative; 4-(1H-Pyrazolo[3,4-b]pyridin-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yl)-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality commitment supports applications requiring high standards, including GMP-grade material for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.