Description

4,6-Dichloro-2-Methylnicotinonitrile is a high-value, halogenated pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure makes it an essential building block for constructing complex heterocyclic compounds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP or ISO standards.

Basic Information

Product Name	4,6-Dichloro-2-Methylnicotinonitrile
CAS No.	1185190-81-1
Molecular Formula	C7H4Cl2N2
Molecular Weight	187.03 g/mol
Synonyms	2-Methyl-4,6-dichloronicotinonitrile; 4,6-Dichloro-2-methyl-3-pyridinecarbonitrile; 3-Cyano-4,6-dichloro-2-methylpyridine; 2-Methyl-4,6-dichloro-3-cyanopyridine; Nicotinonitrile, 4,6-dichloro-2-methyl-; 4,6-Dichloro-2-methylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Methylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with standards applicable to fine chemical and pharmaceutical intermediate production, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.