Description

1-(2-Amino-1-(Pyridin-4-Yl)Ethyl)-4-(Trifluoromethyl)Piperidin-4-Ol Hcl is a high-purity, advanced pharmaceutical intermediate featuring a complex piperidine-pyridine hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting the central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique piperidine-pyridine scaffold.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global biopharma clients.
• Academic Research: Used in university and institutional laboratories for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	1-(2-Amino-1-(Pyridin-4-Yl)Ethyl)-4-(Trifluoromethyl)Piperidin-4-Ol Hcl
CAS No.	1185160-84-2
Molecular Formula	C14H19ClF3N3O
Molecular Weight	337.77 g/mol
Synonyms	1-(2-Amino-1-(4-Pyridyl)ethyl)-4-(trifluoromethyl)-4-piperidinol hydrochloride; 4-(Trifluoromethyl)-1-[2-amino-1-(4-pyridinyl)ethyl]-4-piperidinol hydrochloride; 1-(2-Amino-1-(pyridin-4-yl)ethyl)-4-(trifluoromethyl)piperidin-4-ol hydrochloride; 1185160-84-2; 4-Piperidinol, 1-[2-amino-1-(4-pyridinyl)ethyl]-4-(trifluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-1-(Pyridin-4-Yl)Ethyl)-4-(Trifluoromethyl)Piperidin-4-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.