Description

3-Pyridinemethanamine, 4-(Trifluoromethyl)-, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core substituted with a trifluoromethyl group and an aminomethyl side chain. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation drugs, including kinase inhibitors and other small-molecule therapeutics. Its precise chemical structure, identified by CAS No. 1185138-23-1, enables targeted molecular modifications essential for modern drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for targeted cancer therapies and kinase inhibitors.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced crop protection agents and herbicides, leveraging the biological activity of the trifluoromethylpyridine moiety.
• Ligand & Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential building block for functionalized polymers and advanced organic electronic materials.

Basic Information

Product Name	3-Pyridinemethanamine, 4-(Trifluoromethyl)-, Hydrochloride (1:1)
CAS No.	1185138-23-1
Molecular Formula	C7H8F3N2·HCl
Molecular Weight	216.61 g/mol
Synonyms	4-(Trifluoromethyl)pyridin-3-ylmethanamine hydrochloride; [4-(Trifluoromethyl)pyridin-3-yl]methanamine hydrochloride; 3-(Aminomethyl)-4-(trifluoromethyl)pyridine hydrochloride; 4-(Trifluoromethyl)-3-pyridinemethanamine hydrochloride; 3-Pyridinemethanamine, 4-(trifluoromethyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanamine, 4-(Trifluoromethyl)-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' pharmaceutical and advanced R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.