Description

2',4',6',7'-Tetrahydrospiro[1,3-Dioxolane-2,5'-Indazole] Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant interest for its role as a key building block in the synthesis of novel therapeutic agents, particularly within medicinal chemistry research and development. It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Research: Used as a tool compound in biochemical assays and pharmacological studies to investigate specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and chemical biology projects.

Basic Information

Product Name	2',4',6',7'-Tetrahydrospiro[1,3-Dioxolane-2,5'-Indazole] Hydrochloride
CAS No.	1185012-60-5
Molecular Formula	C11H13N3O2 • HCl
Molecular Weight	255.70 g/mol
Synonyms	2',4',6',7'-Tetrahydrospiro[1,3-dioxolane-2,5'-indazole] hydrochloride; 2H-Indazole, 4,5,6,7-tetrahydro-2-(1,3-dioxolan-2-yl)-, hydrochloride (1:1); Spiro[1,3-dioxolane-2,5'-4,5,6,7-tetrahydro-2H-indazole] hydrochloride; Tetrahydrospiro[dioxolane-indazole] HCl; 1185012-60-5; CAS 1185012-60-5
EINECS	Contact for details

Quality Control

Our 2',4',6',7'-Tetrahydrospiro[1,3-Dioxolane-2,5'-Indazole] Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.