Description

5-Bromo-4-Chloro-2-Fluoropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides requiring halogenated heterocyclic cores.
• Material Science Research: Serves as a monomer or functionalization agent for creating specialized polymers and liquid crystals.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive halogen sites for bioconjugation.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Fluoropyridine
CAS No.	1184920-15-7
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	4-Chloro-5-bromo-2-fluoropyridine; 2-Fluoro-4-chloro-5-bromopyridine; 5-Bromo-4-chloro-2-fluoro-pyridine; Pyridine, 5-bromo-4-chloro-2-fluoro-; 1184920-15-7; 2-Fluoropyridine, 5-bromo-4-chloro-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Chloro-2-Fluoropyridine is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC/GC and NMR data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.