Description

2-Fluoro-5-Iodo-4-Methylpyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Incorporated into the design of organic electronic materials, liquid crystals, and photoactive compounds.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form biaryl systems.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes.

Basic Information

Item	Details
Product Name	2-Fluoro-5-Iodo-4-Methylpyridine
CAS No.	1184913-75-4
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	4-Methyl-2-fluoro-5-iodopyridine; 5-Iodo-2-fluoro-4-methylpyridine; 2-Fluoro-4-methyl-5-iodopyridine; 5-Iodo-4-methyl-2-fluoropyridine; 1184913-75-4; 2-Fluoro-5-iodo-4-picoline; 4-Methyl-5-iodo-2-fluoropyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodo-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.