Description

Methyl 1-(2-Bromoacetyl)Cyclopropanecarboxylate is a high-value, multifunctional cyclopropane derivative used as a key synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a reactive bromoacetyl group and a cyclopropane ring, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those containing cyclopropane motifs, which are valued for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane ring can enhance biological activity.
• Chemical Biology Probe Development: Serves as a starting material for creating molecular probes and tool compounds used to study biological pathways and protein function.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored properties, leveraging the strain energy of the cyclopropane ring.
• Cross-Coupling Reactions: The bromoacetyl moiety acts as an excellent electrophile for various palladium-catalyzed cross-coupling reactions, enabling rapid diversification of molecular scaffolds.
• Academic & Contract Research: A valuable reagent for methodology development and complex natural product synthesis in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	Methyl 1-(2-Bromoacetyl)Cyclopropanecarboxylate
CAS No.	1184913-42-5
Molecular Formula	C7H9BrO3
Molecular Weight	221.05 g/mol
Synonyms	Methyl 2-bromo-1-cyclopropanecarbonylacetate; 1-(2-Bromoacetyl)cyclopropanecarboxylic acid methyl ester; Methyl 1-(bromoacetyl)cyclopropanecarboxylate; Bromoacetyl cyclopropanecarboxylate methyl ester; Cyclopropanecarboxylic acid, 1-(bromoacetyl)-, methyl ester; (2-Bromoacetyl)cyclopropanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 1-(2-Bromoacetyl)Cyclopropanecarboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.