Description

4-(4-Nitrophenoxy)Pyridine-2-Carboxylic Acid is a high-purity organic intermediate featuring a pyridine core substituted with both a carboxylic acid and a nitrophenoxy group. This unique bifunctional structure makes it a versatile building block for synthesizing more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the creation of novel active compounds, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting specific enzymes or receptors.
• Agrochemical Research: Serves as a critical scaffold for developing new herbicides, fungicides, or insecticides with modified activity and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs) due to its chelating carboxylic acid and aromatic nitrogen sites.
• Material Science: Building block for creating functional polymers or organic electronic materials where the nitro and acid groups can be further modified.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	4-(4-Nitrophenoxy)Pyridine-2-Carboxylic Acid
CAS No.	1184827-15-3
Molecular Formula	C12H8N2O5
Molecular Weight	260.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-(4-nitrophenoxy)-; 4-(4-Nitrophenoxy)picolinic acid; 4-(p-Nitrophenoxy)-2-pyridinecarboxylic acid; 4-(4-Nitro-phenoxy)-pyridine-2-carboxylic acid; Picolinic acid, 4-(4-nitrophenoxy)-; CAS 1184827-15-3
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrophenoxy)Pyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.