Description

2-Amino-3-Chloro-5-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. This compound matters for its role as a critical building block in the development of complex, high-value molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research and development chemists, process development scientists, and manufacturers in the fine chemical industry who require reliable, high-quality intermediates for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its substituted aniline structure.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) working on proprietary compounds.
• Academic and Industrial R&D: Used in research laboratories for methodological development and exploring new chemical reactions involving halogenated aniline derivatives.

Basic Information

Product Name	2-Amino-3-Chloro-5-Fluoro-Benzoic Acid Methyl Ester
CAS No.	1184351-57-2
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	Methyl 2-Amino-3-Chloro-5-Fluorobenzoate; Benzoic acid, 2-amino-3-chloro-5-fluoro-, methyl ester; 3-Chloro-5-fluoroanthranilic acid methyl ester; Methyl 3-chloro-5-fluoroanthranilate; 2-Amino-3-chloro-5-fluorobenzoic acid methyl ester; Methyl 2-amino-3-chloro-5-fluorobenzoate; CAS 1184351-57-2
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.