Description

5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methyl]-2-Methyl-Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and ester functionality. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering precise control over molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Peptidomimetic Synthesis: Used to introduce protected amino acid-like structures into molecules designed to mimic peptides.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides a stable, orthogonal protecting group for amines during complex synthetic sequences.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators with tailored properties.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis or metal-organic frameworks.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methyl]-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	1184301-84-5
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	Methyl 5-((((tert-butoxy)carbonyl)amino)methyl)-2-methylbenzoate; 2-Methyl-5-((((tert-butoxy)carbonyl)amino)methyl)benzoic Acid Methyl Ester; Methyl 2-Methyl-5-((((tert-butoxy)carbonyl)amino)methyl)benzoate; 5-((Boc-amino)methyl)-2-methylbenzoic Acid Methyl Ester; Boc-AMB Methyl Ester; tert-Butyl (5-(methoxycarbonyl)-4-methylbenzyl)carbamate; 1184301-84-5
EINECS	Contact for details

Quality Control

Our production of 5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino]Methyl]-2-Methyl-Benzoic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with specifications that can meet research-grade through to cGMP standards, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥98.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.