Description

2,5-Dioxa-8-Aza-Spiro[3,5]Nonane is a high-value, multifunctional spirocyclic building block used in advanced organic synthesis. This compound is crucial for the development of novel pharmaceuticals and agrochemicals due to its unique rigid, three-dimensional structure that can impart desirable biological and physical properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into polymers and advanced materials to modify thermal stability, rigidity, and solubility properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tools for studying biological systems and drug discovery.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	2,5-Dioxa-8-Aza-Spiro[3,5]Nonane
CAS No.	1184185-17-8
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	8-Aza-2,5-dioxaspiro[3.5]nonane; 2,5-Dioxa-8-azaspiro[3.5]nonane; Spiro[1,4-dioxane-2,1'-azetidine]; 1-Oxa-4-azaspiro[2.4]heptane-4-carboxaldehyde, 2,2-dimethyl- (related); Azetidine, 1-(1,4-dioxan-2-yl)-; 1-(1,4-Dioxan-2-yl)azetidine
EINECS	Contact for details

Quality Control

Our 2,5-Dioxa-8-Aza-Spiro[3,5]Nonane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.