Description

2-Fluoro-5-Methylpyridin-3-Ol is a high-purity fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into more complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic and heterocyclic core.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Fluoro-5-Methylpyridin-3-Ol
CAS No.	1184172-53-9
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	3-Hydroxy-2-fluoro-5-methylpyridine; 5-Methyl-2-fluoropyridin-3-ol; 2-Fluoro-5-methyl-3-pyridinol; 2-Fluoro-5-methyl-3-hydroxypyridine; 3-Pyridinol, 2-fluoro-5-methyl-; 2-Fluoro-5-methylpyridin-3-ol; 1184172-53-9
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylpyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures reliable material for your most demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.