Description

2-Chloro-3-Fluoropyridin-4-Ol is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which facilitates the introduction of functional complexity into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	2-Chloro-3-Fluoropyridin-4-Ol
CAS No.	1184172-46-0
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	4-Hydroxy-2-chloro-3-fluoropyridine; 2-Chloro-3-fluoro-4-hydroxypyridine; 2-Chloro-3-fluoro-4-pyridinol; 3-Fluoro-2-chloro-4-pyridinol; 4-Pyridinol, 2-chloro-3-fluoro-; 2-Chloro-3-fluoropyridin-4-ol; 2-Chloro-3-fluoro-4(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoropyridin-4-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.