Description

3-Fluoro-5-Hydroxypyridin-4(1H)-One is a fluorinated pyridinone derivative, a high-value heterocyclic building block prized for its unique electronic and steric properties. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate a fluorine-substituted pyridinone scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the bioactivity of the fluoropyridinone core.
• Ligand Synthesis: Serves as a precursor for creating complexing agents and ligands in coordination chemistry and catalysis.
• Material Science: A building block for organic electronic materials and advanced polymers where fluorine substitution enhances stability and performance.
• Chemical Biology: Employed as a probe or tag in biochemical research due to its distinct structural motif.

Basic Information

Product Name	3-Fluoro-5-Hydroxypyridin-4(1H)-One
CAS No.	1184172-13-1
Molecular Formula	C5H4FNO2
Molecular Weight	129.09 g/mol
Synonyms	4(1H)-Pyridinone, 3-fluoro-5-hydroxy-; 3-Fluoro-5-hydroxypyridin-4(1H)-one; 3-Fluoro-5-hydroxy-4(1H)-pyridinone; 5-Hydroxy-3-fluoropyridin-4(1H)-one; 3-Fluoro-5-hydroxypyridin-4-one; 3-Fluoro-5-hydroxy-1H-pyridin-4-one
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-5-Hydroxypyridin-4(1H)-One adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques like HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.