Description

6-Bromopyridin-2-Amine is a versatile brominated pyridine derivative serving as a critical building block in advanced organic synthesis. This high-purity intermediate is essential for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form C-C and C-N bonds.
• Chemical Biology Probes: Used to create labeled compounds and molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	6-Bromopyridin-2-Amine
CAS No.	1184170-10-2
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	2-Amino-6-bromopyridine; 6-Bromo-2-pyridinamine; 6-Bromo-2-aminopyridine; 2-Pyridinamine, 6-bromo-; 6-Bromopyridin-2-ylamine; 6-Bromo-2-pyridylamine; 2-Amino-6-bromo-pyridine; 6-Brom-2-pyridylamin
EINECS	Contact for details

Quality Control

Our 6-Bromopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.