Description

2-(4-Bromo-1H-Pyrazol-1-Yl)Isonicotinonitrile is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular structure, featuring both pyrazole and isonicotinonitrile moieties, makes it an invaluable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other biologically active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with specific modes of action.
• Ligand Synthesis: Serves as a versatile scaffold for creating novel ligands in catalysis and metal-organic framework (MOF) research.
• Material Science: Employed in the synthesis of functional organic materials, including organic light-emitting diodes (OLEDs) and electronic chemicals.
• Chemical Biology Probe: Utilized as a core structure for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2-(4-Bromo-1H-Pyrazol-1-Yl)Isonicotinonitrile
CAS No.	1183746-57-7
Molecular Formula	C9H5BrN4
Molecular Weight	249.07 g/mol
Synonyms	2-(4-Bromo-1H-pyrazol-1-yl)isonicotinonitrile; 4-Bromo-1-(4-cyano-2-pyridyl)pyrazole; 1-(4-Cyanopyridin-2-yl)-4-bromo-1H-pyrazole; 2-(4-Bromopyrazol-1-yl)isonicotinonitrile; Isonicotinonitrile, 2-(4-bromo-1H-pyrazol-1-yl)-; 1183746-57-7; 4-Bromo-1-(4-cyanopyridin-2-yl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-1H-Pyrazol-1-Yl)Isonicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.