Description

n-((5-Bromopyridin-3-Yl)Methyl)Butan-2-Amine is a high-purity brominated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both a bromine substituent and a secondary amine functional group into target molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized for designing and synthesizing molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	n-((5-Bromopyridin-3-Yl)Methyl)Butan-2-Amine
CAS No.	1183693-62-0
Molecular Formula	C10H15BrN2
Molecular Weight	243.15 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)-N-sec-butylmethanamine; 2-Butanamine, N-[(5-bromo-3-pyridinyl)methyl]-; (5-Bromopyridin-3-yl)methyl(sec-butyl)amine; sec-Butyl(5-bromopyridin-3-yl)methylamine; N-[(5-Bromopyridin-3-yl)methyl]butan-2-amine; 3-[(sec-Butylamino)methyl]-5-bromopyridine
EINECS	Contact for details

Quality Control

Our n-((5-Bromopyridin-3-Yl)Methyl)Butan-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.