Description

4-(3-Hydroxyphenoxy)Pyridine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1183665-90-8. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its bifunctional phenoxy and carboxamide groups.
• Research & Development (R&D): Serves as a standard or reagent in academic and industrial laboratories for method development and biochemical research.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and herbicides.
• Material Science: Can be investigated for incorporation into specialty polymers or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(3-Hydroxyphenoxy)Pyridine-2-Carboxamide
CAS No.	1183665-90-8
Molecular Formula	C12H10N2O3
Molecular Weight	230.22 g/mol
Synonyms	4-(3-Hydroxyphenoxy)picolinamide; 2-Pyridinecarboxamide, 4-(3-hydroxyphenoxy)-; 4-(3-Hydroxy-phenoxy)-pyridine-2-carboxylic acid amide; Picolinamide, 4-(3-hydroxyphenoxy)-; 1183665-90-8; 4-(3-Hydroxyphenoxy)-2-pyridinecarboxamide; 4-(m-Hydroxyphenoxy)picolinamide
EINECS	Contact for details

Quality Control

Our 4-(3-Hydroxyphenoxy)Pyridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.