Description

(2-Chloro-Pyridin-3-Yl)-(2-Hydroxymethyl-Piperidin-1-Yl)-Methanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small-molecule drugs.
• Contract Development & Manufacturing (CDMO): Sourced for custom synthesis projects and scale-up from gram to kilogram quantities.
• Agrochemical Research: Serves as a precursor in the development of new generation pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	(2-Chloro-Pyridin-3-Yl)-(2-Hydroxymethyl-Piperidin-1-Yl)-Methanone
CAS No.	1183142-33-7
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	1-[(2-Chloropyridin-3-yl)carbonyl]-2-(hydroxymethyl)piperidine; (2-Chloro-3-pyridinyl)[2-(hydroxymethyl)-1-piperidinyl]methanone; 2-Chloro-N-(2-(hydroxymethyl)piperidin-1-yl)nicotinamide; 1183142-33-7; Methanone, (2-chloro-3-pyridinyl)[2-(hydroxymethyl)-1-piperidinyl]-
EINECS	Contact for details

Quality Control

Every batch of (2-Chloro-Pyridin-3-Yl)-(2-Hydroxymethyl-Piperidin-1-Yl)-Methanone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for use in GMP and non-GMP development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.