Description

5-Amino-Nicotinic Acid Methyl Ester Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate. This compound is critical for the synthesis of complex molecules, offering a versatile pyridine scaffold with both amino and ester functionalities. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of compounds for high-throughput screening.
• Academic & R&D: Essential for medicinal chemistry research and process development in university and corporate laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a defined, high-purity pyridine derivative.

Basic Information

Item	Detail
Product Name	5-Amino-Nicotinic Acid Methyl Ester Hydrochloride
CAS No.	1182721-48-7
Molecular Formula	C7H9N2O2·HCl
Molecular Weight	188.62 g/mol
Synonyms	Methyl 5-aminonicotinate hydrochloride; 5-Amino-3-pyridinecarboxylic acid methyl ester hydrochloride; Methyl 5-aminopyridine-3-carboxylate hydrochloride; 3-Carbomethoxy-5-aminopyridine hydrochloride; 5-Aminonicotinic acid methyl ester HCl; 5-Amino-3-(methoxycarbonyl)pyridine hydrochloride; 3-Pyridinecarboxylic acid, 5-amino-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-Nicotinic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.