Description

4-(2-(Thiophen-2-Yl)Ethoxy)Pyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure combining pyridinone and thiophene moieties. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and protein function.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.
• Library Synthesis: An important component for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	4-(2-(Thiophen-2-Yl)Ethoxy)Pyridin-2(1H)-One
CAS No.	1182255-11-3
Molecular Formula	C11H11NO2S
Molecular Weight	221.28 g/mol
Synonyms	4-[2-(Thiophen-2-yl)ethoxy]pyridin-2(1H)-one; 2(1H)-Pyridinone, 4-[2-(2-thienyl)ethoxy]-; 4-(2-Thienylethoxy)-2(1H)-pyridinone; 4-(2-Thiophen-2-ylethoxy)-1H-pyridin-2-one; 1182255-11-3; 4-(2-(Thiophen-2-yl)ethoxy)-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

Our 4-(2-(Thiophen-2-Yl)Ethoxy)Pyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.