Description

[3-(Pyridin-4-Yl)-1,2,4-Oxadiazol-5-Yl]Methanamine Dihydrochloride is a high-purity, heterocyclic organic compound with the CAS number 1181458-05-8. This specialized building block is critical for advanced research and development in medicinal chemistry, offering a versatile scaffold for creating novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and academic research institutions focused on drug discovery and chemical biology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to identify new bioactive compounds.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study enzyme function and biological pathways.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Product Name	[3-(Pyridin-4-Yl)-1,2,4-Oxadiazol-5-Yl]Methanamine Dihydrochloride
CAS No.	1181458-05-8
Molecular Formula	C8H9N4O • 2HCl
Molecular Weight	249.10 g/mol (Free base: 177.19 g/mol)
Synonyms	5-(Aminomethyl)-3-(4-pyridinyl)-1,2,4-oxadiazole dihydrochloride; 3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-ylmethanamine dihydrochloride; (3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methanamine hydrochloride (1:2); 1181458-05-8; 4-Pyridyl-oxadiazole amine dihydrochloride
EINECS	Contact for details

Quality Control

Our [3-(Pyridin-4-Yl)-1,2,4-Oxadiazol-5-Yl]Methanamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.