Description

5-(3-Hydroxyphenyl)-Nicotinic Acid is a high-purity organic compound featuring a biphenyl core structure with both hydroxyphenyl and nicotinic acid functional groups. This unique molecular architecture makes it a valuable pharmaceutical intermediate and research chemical for the synthesis of complex bioactive molecules. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Serves as a precursor for developing new active ingredients in crop protection and plant growth regulation.
• Ligand & Chelating Agent: Used in coordination chemistry and catalysis research due to its multifunctional donor sites.
• Material Science: Intermediate for creating specialized polymers and organic electronic materials.
• Biochemical Research: Tool compound for studying enzyme inhibition and receptor binding activities in vitro.
• Custom Synthesis: Starting material for contract research organizations (CROs) and fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	5-(3-Hydroxyphenyl)-Nicotinic Acid
CAS No.	1181452-05-0
Molecular Formula	C12H9NO3
Molecular Weight	215.20 g/mol
Synonyms	3-Hydroxy-5-phenylnicotinic Acid; 5-(3-Hydroxyphenyl)pyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 5-(3-hydroxyphenyl)-; 5-(3-Hydroxyphenyl)nicotinic Acid; 3-Hydroxy-5-phenyl-3-pyridinecarboxylic Acid; 5-(m-Hydroxyphenyl)nicotinic Acid
EINECS	Contact for details

Quality Control

Our 5-(3-Hydroxyphenyl)-Nicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material is suitable for demanding research and development and GMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.