Description

3-Bromo-5-[4-(Trifluoromethoxy)Phenyl]-Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both bromine and trifluoromethoxy substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	3-Bromo-5-[4-(Trifluoromethoxy)Phenyl]-Pyridine
CAS No.	1181214-52-7
Molecular Formula	C12H7BrF3NO
Molecular Weight	318.09 g/mol
Synonyms	3-Bromo-5-(4-(trifluoromethoxy)phenyl)pyridine; 5-Bromo-3-(4-(trifluoromethoxy)phenyl)pyridine; [4-(Trifluoromethoxy)phenyl]-5-bromopyridine; 3-Bromo-5-(4-trifluoromethoxyphenyl)pyridine; Pyridine, 3-bromo-5-[4-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-[4-(Trifluoromethoxy)Phenyl]-Pyridine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.