Description

Methyl 2-(5-Chloropyridin-2-Yl)Acetate CAS NO 1181210-76-3 is a high-purity, versatile pyridine derivative ester that serves as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular structure, which enables the efficient construction of complex pharmacophores and agrochemical intermediates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the chloropyridine moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	Methyl 2-(5-Chloropyridin-2-Yl)Acetate
CAS No.	1181210-76-3
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Methyl (5-chloropyridin-2-yl)acetate; 2-(5-Chloro-2-pyridinyl)acetic acid methyl ester; Methyl 2-(5-chloro-2-pyridyl)acetate; (5-Chloropyridin-2-yl)acetic acid methyl ester; 5-Chloro-2-pyridineacetic acid methyl ester; Methyl 5-chloropyrid-2-ylacetate; 1181210-76-3
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Chloropyridin-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.