Description

5-Bromo-2-Iodopyridin-3-Amine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique bifunctional halogen pattern makes it an indispensable intermediate for constructing complex heterocyclic scaffolds. This compound is primarily sought after by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of both bromo and iodo substituents.
• Ligand and Catalyst Development: Employed in the creation of novel nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, affinity labels, and other molecular probes in life sciences research.

Basic Information

Product Name	5-Bromo-2-Iodopyridin-3-Amine
CAS No.	1180678-40-3
Molecular Formula	C5H4BrIN2
Molecular Weight	298.91 g/mol
Synonyms	3-Amino-5-bromo-2-iodopyridine; 5-Bromo-2-iodo-3-pyridinamine; 2-Iodo-5-bromopyridin-3-amine; 3-Pyridinamine, 5-bromo-2-iodo-; 5-Bromo-2-iodo-3-aminopyridine; 1180678-40-3; 5-Br-2-I-3-NH2-Py
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodopyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.