Description

6-(Trifluoromethyl)-[1,2,4]Triazolo[4,3-A]Pyridin-3-Amine is a high-value, nitrogen-rich heterocyclic compound featuring a trifluoromethyl group, a key structural motif in modern pharmaceutical and agrochemical research. This compound matters as a sophisticated building block for medicinal chemistry, enabling the development of novel active ingredients with enhanced metabolic stability and bioavailability. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced material sectors for creating new drug candidates, crop protection agents, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug discovery programs.
• Agrochemical Research: Used as a key precursor in developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolopyridine core.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Investigated as a monomer or additive for creating advanced polymers and electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	6-(Trifluoromethyl)-[1,2,4]Triazolo[4,3-A]Pyridin-3-Amine
CAS No.	1180519-29-2
Molecular Formula	C7H5F3N4
Molecular Weight	202.14 g/mol
Synonyms	6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine; 6-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridin-3-amine; 1180519-29-2; 3-Amino-6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridine; 6-Trifluoromethyl-[1,2,4]triazolo[4,3-a]pyridin-3-ylamine; 6-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-[1,2,4]Triazolo[4,3-A]Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.