Description

5-((4-Ethylpiperazin-1-Yl)Methyl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine-pyridine hybrid scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemists to explore new structure-activity relationships (SAR) and create focused libraries.
• API Synthesis: Used in the multi-step manufacturing process of complex active pharmaceutical ingredients (APIs) for preclinical and clinical studies.
• Ligand Synthesis: Employed in the development of selective ligands for various receptor subtypes due to its piperazine moiety.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and the development of new therapeutic concepts.

Basic Information

Product Name	5-((4-Ethylpiperazin-1-Yl)Methyl)Pyridin-2-Amine
CAS No.	1180132-17-5
Molecular Formula	C12H20N4
Molecular Weight	220.32 g/mol
Synonyms	2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine; 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine; 2-Pyridinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-; 5-((4-Ethylpiperazin-1-yl)methyl)-2-aminopyridine; 5-[(4-Ethylpiperazin-1-yl)methyl]-2-aminopyridine; 5-(4-Ethylpiperazin-1-ylmethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 5-((4-Ethylpiperazin-1-Yl)Methyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.