Description

1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, Ethanedioate (1:1) is a high-purity, protected spirocyclic amine building block essential for advanced organic synthesis. This compound is valued for its rigid, three-dimensional structure, which is critical for modulating the physicochemical properties and biological activity of target molecules in pharmaceutical research. It is primarily used by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Medicinal Chemistry: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve metabolic stability, solubility, and selectivity of lead compounds.
• Peptidomimetics: Serves as a non-natural amino acid analog for the design of peptide-like molecules with enhanced pharmacological profiles.
• Agrochemical Research: Employed in the synthesis of new active ingredients for crop protection, leveraging its unique spirocyclic geometry.
• Chemical Biology: Utilized as a molecular probe or linker in the development of chemical tools for studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in bespoke synthesis projects for clients.

Basic Information

Product Name	1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, Ethanedioate (1:1)
CAS No.	1180112-42-8
Molecular Formula	C14H24N2O6
Molecular Weight	316.35 g/mol
Synonyms	tert-Butyl 1,7-diazaspiro[3.5]nonane-7-carboxylate oxalate (1:1); 1,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 1,1-dimethylethyl ester, ethanedioate; Boc-1,7-Diazaspiro[3.5]nonane Oxalate Salt; 7-(tert-Butoxycarbonyl)-1,7-diazaspiro[3.5]nonane oxalate; 1,1-Dimethylethyl 1,7-diazaspiro[3.5]nonane-7-carboxylate ethanedioate; Spirocyclic Amine Boc-Protected Oxalate Salt
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[3.5]Nonane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, Ethanedioate (1:1) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.