Description

2-(Methylamino)Pyridin-3-Yl)Methyl 2-((tert-Butoxycarbonyl)(Methyl)Amino)Acetate is a sophisticated, high-purity chemical intermediate designed for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, offering a protected amine functionality essential for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptidomimetic Synthesis: Used to introduce protected amino acid analogs into peptide chains, enabling the creation of stable, bioavailable peptide-like molecules.
• Protecting Group Chemistry: Serves as a reagent featuring a tert-butoxycarbonyl (Boc) protected methylamino group, crucial for selective reactions in complex organic syntheses.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for molecular diversification.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Bioconjugation: Potential use in linking small molecule payloads to larger carriers like antibodies or polymers in targeted drug delivery systems.

Basic Information

Product Name	2-(Methylamino)Pyridin-3-Yl)Methyl 2-((tert-Butoxycarbonyl)(Methyl)Amino)Acetate
CAS No.	1180002-01-0
Molecular Formula	C15H23N3O4
Molecular Weight	309.36 g/mol
Synonyms	Boc-N(Me)-Gly-O-CH2-3-(MeNH)Pyridine; 2-[(tert-Butoxycarbonyl)(methyl)amino]acetic acid [2-(methylamino)-3-pyridyl]methyl ester; [2-(Methylamino)-3-pyridinyl]methyl N-[(1,1-dimethylethoxy)carbonyl]-N-methylglycinate; N-Boc-N-methylglycine (2-(methylamino)pyridin-3-yl)methyl ester; tert-Butyl [methyl[(2-{[2-(methylamino)-3-pyridinyl]methoxy}-2-oxoethyl)amino]carbonate; (2-(Methylamino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate
EINECS	Contact for details

Quality Control

Our production of 2-(Methylamino)Pyridin-3-Yl)Methyl 2-((tert-Butoxycarbonyl)(Methyl)Amino)Acetate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider using desiccants and maintaining an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.