Description

1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)-3-Methylbutan-1-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new APIs, especially within the [1,2,4]triazolo[4,3-a]pyridine chemical class.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.

Basic Information

Product Name	1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)-3-Methylbutan-1-Amine Hydrochloride
CAS No.	1179491-42-9
Molecular Formula	C11H15N4•HCl
Molecular Weight	238.72 g/mol
Synonyms	1-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)-3-methylbutan-1-amine hydrochloride; 3-(3-Methylbutyl)-[1,2,4]triazolo[4,3-a]pyridin-1-ium chloride; 1-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)-3-methylbutylamine hydrochloride; 1,2,4-Triazolo[4,3-a]pyridine, 3-(3-methylbutyl)-, hydrochloride; 3-(3-Methylbutyl)-1,2,4-triazolo[4,3-a]pyridin-1-ium chloride
EINECS	Contact for details

Quality Control

Our 1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)-3-Methylbutan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.