Description

6-(Bromomethyl)Picolinimidamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive bromomethyl and amidine functional groups. This compound is critical for medicinal chemists as a versatile building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small molecule therapeutics, where precise chemical structure and reliable purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for constructing molecular libraries in drug discovery programs, especially for protease and kinase inhibitors.
• Chemical Biology Probes: Employed in the development of activity-based probes (ABPs) and other tools for studying enzyme function and target engagement.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents and pesticides.
• Material Science: Investigated for the preparation of functionalized polymers or ligands for catalytic systems.

Basic Information

Product Name	6-(Bromomethyl)Picolinimidamide Hydrochloride
CAS No.	1179362-86-7
Molecular Formula	C7H9BrClN3
Molecular Weight	250.52 g/mol
Synonyms	6-(Bromomethyl)-2-pyridinecarboximidamide hydrochloride; 2-Amidino-6-(bromomethyl)pyridine hydrochloride; Picolinimidamide, 6-(bromomethyl)-, hydrochloride; 6-(Bromomethyl)pyridine-2-carboximidamide hydrochloride; (6-(Bromomethyl)pyridin-2-yl)methanimidamide hydrochloride
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)Picolinimidamide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.