Description

3-Chloro-5-(Trifluoromethyl)Picolinimidamide Hydrochloride is a high-value, halogenated pyridine derivative used as a critical synthetic intermediate in advanced chemical synthesis. This compound is essential for researchers and manufacturers developing novel active ingredients, particularly in the pharmaceutical and agrochemical sectors. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a versatile building block for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science Research: Investigated as a monomer or functionalizing agent for creating specialty polymers and advanced materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library development.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethyl)Picolinimidamide Hydrochloride
CAS No.	1179362-45-8
Molecular Formula	C7H6ClF3N3·HCl
Molecular Weight	276.50 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)pyridine-2-carboximidamide hydrochloride; 2-Pyridinecarboximidamide, 3-chloro-5-(trifluoromethyl)-, hydrochloride (1:1); 3-Chloro-5-trifluoromethylpicolinimidamide HCl; 3-Chloro-5-(trifluoromethyl)picolinamidine hydrochloride; 1179362-45-8; 3-Chloro-5-(trifluoromethyl)-2-pyridinecarboximidamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethyl)Picolinimidamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory starting material documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.