Description

4-Methylpicolinimidamide Hydrochloride is a high-purity chemical intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a versatile building block for the synthesis of complex heterocyclic compounds, particularly in pharmaceutical research and development. This product is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile reagent for constructing complex nitrogen-containing heterocycles like imidazoles and fused pyridine derivatives.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Institutional R&D: A valuable compound for universities and research institutes conducting fundamental studies in organic and medicinal chemistry.
• Scale-up and Process Chemistry: Suitable for process optimization and pilot-scale synthesis under current Good Manufacturing Practice (cGMP) guidelines for advanced pharmaceutical intermediates.

Basic Information

Product Name	4-Methylpicolinimidamide Hydrochloride
CAS No.	1179360-90-7
Molecular Formula	C7H10ClN3
Molecular Weight	171.63 g/mol
Synonyms	4-Methylpyridine-2-carboximidamide hydrochloride; 2-Pyridinecarboximidamide, 4-methyl-, hydrochloride; 4-Methylpicolinamidine hydrochloride; 4-Methyl-2-pyridinecarboximidamide monohydrochloride; 4-Methyl-2-pyridylamidine hydrochloride; Picolinimidamide, 4-methyl-, hydrochloride; 4-Methyl-2-carbamimidoylpyridinium chloride
EINECS	Contact for details

Quality Control

Our 4-Methylpicolinimidamide Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity by HPLC, and identification. Our quality management system supports production to meet the stringent requirements of pharmaceutical intermediate development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.