Description

tert-Butyl 7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its structural complexity and versatility in drug discovery. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	tert-Butyl 7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate
CAS No.	1179338-65-8
Molecular Formula	C14H26N2O3
Molecular Weight	270.37 g/mol
Synonyms	3-[(1,1-Dimethylethoxy)carbonyl]-7-oxa-3,10-diazaspiro[5.6]dodecane; tert-Butyl 7-oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylate; 7-Oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylic acid, 1,1-dimethylethyl ester; 3-Boc-7-oxa-3,10-diazaspiro[5.6]dodecane; Boc-7-oxa-3,10-diazaspiro[5.6]dodecane; 1179338-65-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.