Description

tert-Butyl 9-Oxo-7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate CAS NO 1179338-64-7 is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Integral in the production route for potential Active Pharmaceutical Ingredients (APIs) requiring a spirocyclic core structure.
• Process Development & Scale-Up: Employed in optimizing synthetic pathways from laboratory scale to pilot and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and development.

Basic Information

Product Name	tert-Butyl 9-Oxo-7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate
CAS No.	1179338-64-7
Molecular Formula	C14H24N2O4
Molecular Weight	284.35 g/mol
Synonyms	tert-Butyl 9-oxo-7-oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylate; 3,10-Diazaspiro[5.6]dodecane-3-carboxylic acid, 9-oxo-7-oxa-, 1,1-dimethylethyl ester; 7-Oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylic acid, 9-oxo-, 1,1-dimethylethyl ester; 9-Oxo-7-oxa-3,10-diazaspiro[5.6]dodecane-3-carboxylic acid tert-butyl ester; BOC-protected spirocyclic amino ester; Spirocyclic BOC-amine intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl 9-Oxo-7-Oxa-3,10-Diazaspiro[5.6]Dodecane-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.