Description

tert-Butyl 5-Amino-2-Chlorobenzoate is a high-purity, advanced pharmaceutical intermediate characterized by its amino and chloro functional groups on a benzoate ester scaffold. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and commercial-scale production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Reagent: Used in research laboratories for constructing complex molecules, including dyes, pigments, and functional materials.
• Chemical Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) and optimizing lead compounds.
• Custom Synthesis Projects: Employed in contract manufacturing for the production of tailored, high-value specialty chemicals.

Basic Information

Product Name	tert-Butyl 5-Amino-2-Chlorobenzoate
CAS No.	1179133-92-6
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	5-Amino-2-chlorobenzoic acid tert-butyl ester; Benzoic acid, 5-amino-2-chloro-, 1,1-dimethylethyl ester; 2-Chloro-5-aminobenzoic acid tert-butyl ester; tert-Butyl 5-amino-2-chlorobenzoate; 1,1-Dimethylethyl 5-amino-2-chlorobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Amino-2-Chlorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.