Description

5-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoroethyl-substituted dihydropyridinone core, which is a valuable scaffold for introducing fluorine motifs into target molecules, thereby modulating their physicochemical and biological properties. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, as well as by fine chemical manufacturers producing high-value intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the trifluoroethyl group can enhance metabolic stability and bioavailability.
• Fluorine Chemistry: Serves as a versatile precursor for introducing the 2,2,2-trifluoroethyl moiety into complex molecular architectures in medicinal and materials chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, specialized intermediates for various industrial applications.

Basic Information

Product Name	5-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one
CAS No.	1179038-34-6
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	5-Amino-1-(2,2,2-trifluoroethyl)-2(1H)-pyridinone; 5-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydro-2-pyridone; 1-(2,2,2-Trifluoroethyl)-5-amino-1,2-dihydropyridin-2-one; 5-Amino-1-(trifluoroethyl)dihydropyridin-2-one; 2(1H)-Pyridinone, 5-amino-1-(2,2,2-trifluoroethyl)-; 5-Amino-1-(2,2,2-trifluoroethyl)-2-pyridone
EINECS	Contact for details

Quality Control

Our 5-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and development, and specifications can be aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.