Description

Ponezumab CAS NO 1178862-65-1 is a humanized monoclonal antibody designed for targeted therapeutic applications. This compound is of significant interest in advanced pharmaceutical research and development due to its specific biological activity. It is primarily utilized by biotechnology firms, pharmaceutical manufacturers, and clinical research organizations engaged in the development of novel treatments.

Application

• Pharmaceutical Research & Development (R&D): Used as a key investigational agent in preclinical and clinical studies for targeted therapies.
• Biologics Manufacturing: Serves as an active pharmaceutical ingredient (API) or reference standard in the production of biologic drugs.
• Clinical Diagnostics: Employed in the development of diagnostic assays and biomarker detection kits.
• Academic & Institutional Research: Utilized in university and hospital labs for studying disease mechanisms and antibody functions.
• Process Development & Optimization: Acts as a model molecule for scaling up purification and formulation processes in biomanufacturing.
• Regulatory & Quality Control: Functions as a critical standard for assay validation, stability testing, and regulatory submissions.

Basic Information

Product Name	Ponezumab
CAS No.	1178862-65-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-04360365; RN-1219; Anti-Amyloid Beta Monoclonal Antibody (Ponezumab); Humanized IgG2δa Anti-Aβ Monoclonal Antibody; Ponezumab (USAN/INN); Monoclonal Antibody Ponezumab; Anti-Aβ Antibody Ponezumab
EINECS	Contact for details

Quality Control

Our Ponezumab is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, potency, and consistency. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), endotoxin levels, sterility, and biological activity are available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled, dry conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content	As per COA
Endotoxin	< 1.0 EU/mg
Biological Activity (Binding Assay)	As per COA
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.